# OnCo record cdk12 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cdk12/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cdk12" ;
  schema:name "CDK12"@en ;
  schema:alternateName "cyclin dependent kinase 12"@en, "Cyclin-dependent kinase 12"@en, "CRK7"@en, "KIAA0904"@en, "CRKRS"@en, "CDK12" ;
  schema:description "CDK12 (Cyclin-dependent kinase 12) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor, a biomarker and a fusion partner, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Prostate cancer, Ovarian cancer, Breast cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/cdk12/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:24224>, <https://www.uniprot.org/uniprotkb/Q9NYV4/entry>, <https://www.ncbi.nlm.nih.gov/gene/51755>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000167258> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:24224>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000167258>, <https://www.uniprot.org/uniprotkb/Q9NYV4/entry>, <https://www.ncbi.nlm.nih.gov/gene/51755> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/skin-cancer/> .