# OnCo record cdkn2a-homozygous-deletion (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/cdkn2a-homozygous-deletion/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "cdkn2a-homozygous-deletion" ;
  schema:name "CDKN2A/B homozygous deletion"@en ;
  schema:alternateName "CDKN2A"@en, "CDKN2A deletion"@en, "CDKN2A loss"@en, "CDKN2A/B deletion"@en, "CDKN2A/B homozygous deletion"@en, "9p21 deletion"@en, "9p21 loss"@en, "p16 loss"@en, "MTAP deletion"@en, "CDKN2A/MTAP deletion"@en, "MTAP loss"@en, "MTAP-deleted"@en, "CDKN2A-deleted"@en ;
  schema:description "Losing both copies of the CDKN2A/B genes on chromosome 9p21 removes the cell's main brake on division; in an IDH-mutant glioma it alone makes the tumour grade 4, in mesothelioma and melanoma it marks aggressive disease, and the neighbouring MTAP gene usually goes with it, opening a new drug target."@en ;
  schema:url <https://onco.cc/terms/cdkn2a-homozygous-deletion/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/CDKN2A> ;
  schema:citation <https://en.wikipedia.org/wiki/CDKN2A> ;
  onco:related <https://onco.cc/targets/prmt5-mtap/>, <https://onco.cc/targets/cdk4-6/>, <https://onco.cc/terms/fish/>, <https://onco.cc/technologies/cns-tumour-methylation-classifier/>, <https://onco.cc/terms/1p19q-codeletion/>, <https://onco.cc/terms/bap1-loss/>, <https://onco.cc/terms/hereditary-cancer-syndromes/>, <https://onco.cc/terms/ihc/> ;
  onco:cancers <https://onco.cc/cancers/idh-mutant-astrocytoma/>, <https://onco.cc/cancers/oligodendroglioma/>, <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/meningioma/>, <https://onco.cc/cancers/pleural-mesothelioma/>, <https://onco.cc/cancers/peritoneal-mesothelioma/>, <https://onco.cc/cancers/paediatric-low-grade-glioma/>, <https://onco.cc/cancers/paediatric-high-grade-glioma/>, <https://onco.cc/cancers/malignant-peripheral-nerve-sheath-tumour/>, <https://onco.cc/cancers/myxofibrosarcoma/>, <https://onco.cc/cancers/ewing-sarcoma/>, <https://onco.cc/cancers/richter-transformation-cll/>, <https://onco.cc/cancers/papillary-rcc/>, <https://onco.cc/cancers/undifferentiated-pleomorphic-sarcoma/>, <https://onco.cc/cancers/hpv-negative-head-and-neck-cancer/> .