# OnCo record celecoxib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/celecoxib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "celecoxib" ;
  schema:name "Celecoxib"@en ;
  schema:alternateName "SC-58635"@en, "Celebrex" ;
  schema:description "Celecoxib is a common anti-inflammatory painkiller. In oncology it is paired with low-dose oral methotrexate as a cheap 'metronomic' treatment for advanced head and neck cancer, a regimen from Tata Memorial in Mumbai that beat intravenous cisplatin in a randomised trial."@en ;
  schema:url <https://onco.cc/drugs/celecoxib/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Celecoxib> ;
  schema:citation <https://en.wikipedia.org/wiki/Celecoxib> ;
  onco:status "approved" ;
  onco:tag "subtype-drugs-wave" ;
  onco:modality "Oral COX-2 inhibitor" ;
  onco:approval "US 1998: Osteoarthritis and rheumatoid arthritis pain (oncology use in metronomic regimens is off-label)", "US 1999: Reduction of adenomatous colorectal polyps in familial adenomatous polyposis (accelerated approval; indication withdrawn 2011)" ;
  onco:related <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/nivolumab/> ;
  onco:cancers <https://onco.cc/cancers/oral-cavity-cancer/>, <https://onco.cc/cancers/oral-tongue-cancer/>, <https://onco.cc/cancers/buccal-mucosa-cancer/>, <https://onco.cc/cancers/recurrent-metastatic-hnscc/>, <https://onco.cc/cancers/hpv-negative-head-and-neck-cancer/> ;
  onco:targets <https://onco.cc/targets/cox2/> ;
  onco:companies <https://onco.cc/companies/pfizer/> .