# OnCo record checkmate-648 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/checkmate-648/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "checkmate-648", "NCT03143153" ;
  schema:name "CheckMate 648"@en ;
  schema:description "Showed two immunotherapy options for squamous oesophageal cancer, including one with no chemotherapy at all, both extending survival."@en ;
  schema:url <https://onco.cc/trials/checkmate-648/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03143153>, <https://pubmed.ncbi.nlm.nih.gov/42575473/> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2017-06-29" ;
  onco:cancers <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/oesophageal-squamous-cell-carcinoma/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/ctla4/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/ipilimumab/> ;
  onco:people <https://onco.cc/people/jaffer-ajani/> .