# OnCo record chemo-io-first-line-endometrial (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/chemo-io-first-line-endometrial/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "chemo-io-first-line-endometrial" ;
  schema:name "Chemotherapy + PD-1/PD-L1 blockade, first-line advanced endometrial cancer"@en ;
  schema:description "Three trials with three different antibodies agree: adding immunotherapy to first chemotherapy for advanced endometrial cancer roughly triples progression-free time in dMMR tumours and helps the rest modestly."@en ;
  schema:url <https://onco.cc/pairings/chemo-io-first-line-endometrial/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03981796>, <https://clinicaltrials.gov/study/NCT03914612> ;
  onco:cancers <https://onco.cc/cancers/endometrial/> ;
  onco:drugs <https://onco.cc/drugs/dostarlimab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/durvalumab/> ;
  onco:terms <https://onco.cc/terms/msi/> ;
  onco:trials <https://onco.cc/trials/ruby/>, <https://onco.cc/trials/nrg-gy018-keynote-868/>, <https://onco.cc/trials/duo-e/> ;
  onco:pairs <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/drugs/carboplatin/> .