# OnCo record chemotherapy-roadmap (roadmap). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/roadmaps/chemotherapy-roadmap/>
  a schema:CreativeWork ;
  onco:kind "roadmap" ;
  schema:identifier "chemotherapy-roadmap" ;
  schema:name "Chemotherapy roadmap: mustard gas → curative combinations → the warhead inside smarter drugs"@en ;
  schema:description "Chemotherapy went from a poison that sometimes worked to the backbone of most cures, and is now being given more precisely: to fewer people, at better doses, and increasingly delivered inside an antibody so that it reaches the tumour and not the whole body."@en ;
  schema:url <https://onco.cc/roadmaps/chemotherapy-roadmap/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://www.fda.gov/regulatory-information/search-fda-guidance-documents/optimizing-dosage-human-prescription-drugs-and-biological-products-treatment-oncologic-diseases>, <https://doi.org/10.1158/0008-5472.CAN-07-6611> ;
  onco:related <https://onco.cc/ideas/idea-tr1-pre-emptive-pharmacogenomic-testing/>, <https://onco.cc/ideas/idea-bio2-lean-mass-dosing/>, <https://onco.cc/ideas/idea-reg-metronomic-lmic-phase3-to-label/>, <https://onco.cc/ideas/idea-acc-metronomic-lmic-platform-trial/>, <https://onco.cc/ideas/idea-reg-nonprofit-generic-chemo-manufacturer/>, <https://onco.cc/ideas/idea-reg-generic-chemo-strategic-reserve/>, <https://onco.cc/ideas/idea-moon-neuropathy-prevention-programme/>, <https://onco.cc/ideas/idea-moon-olanzapine-antiemetic-everywhere/>, <https://onco.cc/ideas/idea-moon-hearing-protection-cisplatin/>, <https://onco.cc/ideas/idea-tr1-response-adapted-dose-reduction/>, <https://onco.cc/roadmaps/adc-generations/>, <https://onco.cc/technologies/cannabinoids-nausea/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/g-csf-growth-factors/>, <https://onco.cc/technologies/scalp-cooling/>, <https://onco.cc/technologies/cardio-oncology/>, <https://onco.cc/technologies/pharmacy-automation/>, <https://onco.cc/technologies/infusion-devices-vascular-access/>, <https://onco.cc/technologies/generic-drug-shortage-response/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:drugs <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/docetaxel/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/irinotecan/>, <https://onco.cc/drugs/temozolomide/>, <https://onco.cc/drugs/trastuzumab-deruxtecan/>, <https://onco.cc/drugs/sacituzumab-govitecan/>, <https://onco.cc/drugs/enfortumab-vedotin/>, <https://onco.cc/drugs/sodium-thiosulfate/>, <https://onco.cc/drugs/dexrazoxane/>, <https://onco.cc/drugs/rolapitant/> ;
  onco:trials <https://onco.cc/trials/eortc-26981/>, <https://onco.cc/trials/keynote-024-189/>, <https://onco.cc/trials/checkmate-649/>, <https://onco.cc/trials/cross/>, <https://onco.cc/trials/napoli-3/>, <https://onco.cc/trials/prodige-24/>, <https://onco.cc/trials/interlace/>, <https://onco.cc/trials/echelon-1/>, <https://onco.cc/trials/polarix/>, <https://onco.cc/trials/tailorx/>, <https://onco.cc/trials/rxponder/>, <https://onco.cc/trials/dynamic/>, <https://onco.cc/trials/rathl/>, <https://onco.cc/trials/scarlet-s2212/>, <https://onco.cc/trials/apt-trial/>, <https://onco.cc/trials/ev-302/>, <https://onco.cc/trials/destiny-breast06/>, <https://onco.cc/trials/metronomic-vs-cisplatin-tmh/>, <https://onco.cc/trials/metro-plus-varanasi/>, <https://onco.cc/trials/low-dose-nivolumab-tmh/>, <https://onco.cc/trials/olanzapine-appetite-tmh/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dose-optimisation/>, <https://onco.cc/bottlenecks/b-generic-repurposing/>, <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-global-access/>, <https://onco.cc/bottlenecks/b-cachexia-supportive/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-devita-cancer-res/> .