# OnCo record circadian-control (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/circadian-control/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "circadian-control" ;
  schema:name "Circadian control"@en ;
  schema:description "Cells run on a 24-hour clock that gates cell division, DNA repair, and drug metabolism. Cancers often break their clocks, and the time of day a drug or immunotherapy is given can change how well it works."@en ;
  schema:url <https://onco.cc/pathways/circadian-control/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Chronotherapy_(treatment_scheduling)> ;
  owl:sameAs <http://www.wikidata.org/entity/Q5114262> ;
  schema:citation <https://doi.org/10.1016/S1470-2045(21)00546-5> ;
  onco:tag "mechanism" ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/wee1/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/penn-abramson/> ;
  onco:pathways <https://onco.cc/pathways/p53-cell-cycle/>, <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-qian-lancet-oncol/> .