# OnCo record cl2a (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/cl2a/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "cl2a" ;
  schema:name "CL2A"@en ;
  schema:description "CL2A is the deliberately fragile linker in Trodelvy: it releases SN-38 in the acidic tumour environment as well as inside cells, feeding the bystander effect."@en ;
  schema:url <https://onco.cc/terms/cl2a/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Sacituzumab_govitecan> ;
  schema:citation <https://doi.org/10.1158/1078-0432.CCR-10-2939> ;
  onco:related <https://onco.cc/terms/sn-38/>, <https://onco.cc/terms/bystander-effect/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:drugs <https://onco.cc/drugs/sacituzumab-govitecan/> ;
  onco:terms <https://onco.cc/terms/linker/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-cardillo-clin-cancer-res/> .