# OnCo record claudin-low (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/claudin-low/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "claudin-low" ;
  schema:name "Claudin-low breast cancer"@en ;
  schema:alternateName "Claudin-low subtype"@en, "Claudin-low phenotype"@en, "Claudin-low triple-negative breast cancer"@en ;
  schema:description "Claudin-low breast cancers have lost the claudin proteins that hold epithelial cells together and have taken on the features of migrating, stem-like cells. Most are triple-negative and respond to chemotherapy less well than basal-like cancers. Newer work treats claudin-low as a pattern that can overlay any subtype rather than a subtype of its own."@en ;
  schema:url <https://onco.cc/terms/claudin-low/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Claudin> ;
  schema:citation <https://doi.org/10.1186/bcr2635>, <https://doi.org/10.1038/s41467-020-15574-5>, <https://doi.org/10.1172/jci45014> ;
  onco:tag "breast", "tnbc" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-mesenchymal/>, <https://onco.cc/cancers/tnbc-mesenchymal-stem-like/>, <https://onco.cc/cancers/metaplastic-breast-carcinoma/> ;
  onco:pathways <https://onco.cc/pathways/emt/> ;
  onco:terms <https://onco.cc/terms/basal-like/> .