# OnCo record cldn18-2-expression (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/cldn18-2-expression/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "cldn18-2-expression" ;
  schema:name "Claudin 18.2 expression (>= 75% of tumour cells, moderate to strong)"@en ;
  schema:alternateName "CLDN18.2"@en, "Claudin 18.2 positive"@en, "CLDN18.2-positive"@en, "claudin 18.2 expression"@en, "CLDN18 IHC"@en, "CLDN18.2 >= 75%"@en ;
  schema:description "Claudin 18.2 is a tight-junction protein exposed on stomach cancer cells. Zolbetuximab requires at least 75 percent of tumour cells to stain moderately or strongly, the strictest expression threshold in any current label."@en ;
  schema:url <https://onco.cc/biomarkers/cldn18-2-expression/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e7695a21-abb6-47ac-93f8-0ece5a9c4409> ;
  onco:tag "biomarker", "surface-antigen" ;
  onco:related <https://onco.cc/biomarkers/her2-ihc-3-plus/>, <https://onco.cc/biomarkers/pd-l1-cps/> ;
  onco:cancers <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/gastric-cldn18-2-positive/>, <https://onco.cc/cancers/pancreatic/> ;
  onco:drugs <https://onco.cc/drugs/zolbetuximab/> ;
  onco:terms <https://onco.cc/terms/ihc/> .