# OnCo record cldn18-antibody-then-adc (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/cldn18-antibody-then-adc/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "cldn18-antibody-then-adc" ;
  schema:name "CLDN18.2 antibody first line → CLDN18.2 ADC or CAR-T on progression"@en ;
  schema:description "Hit Claudin 18.2 twice: first with a plain antibody plus chemotherapy, then with an ADC or engineered cells when the cancer comes back."@en ;
  schema:url <https://onco.cc/pairings/cldn18-antibody-then-adc/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03504397>, <https://clinicaltrials.gov/study/NCT06346392> ;
  onco:cancers <https://onco.cc/cancers/gastric/> ;
  onco:targets <https://onco.cc/targets/cldn18-2/> ;
  onco:drugs <https://onco.cc/drugs/zolbetuximab/>, <https://onco.cc/drugs/cmg901/>, <https://onco.cc/drugs/satricabtagene-autoleucel/> ;
  onco:trials <https://onco.cc/trials/spotlight-glow/>, <https://onco.cc/trials/clarity-gastric01/> ;
  onco:pairs <https://onco.cc/drugs/zolbetuximab/>, <https://onco.cc/drugs/cmg901/> .