# OnCo record cldn6 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cldn6/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cldn6" ;
  schema:name "Claudin 6"@en ;
  schema:description "A tight-junction protein normally found only in the embryo that reappears in ovarian, testicular, endometrial and lung cancers, making it a clean target for ADCs and CAR-T."@en ;
  schema:url <https://onco.cc/targets/cldn6/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/CLDN6>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2048>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000184697>, <https://www.uniprot.org/uniprotkb/P56747/entry>, <https://www.ncbi.nlm.nih.gov/gene/9074> ;
  owl:sameAs <http://www.wikidata.org/entity/Q18033805> ;
  schema:citation <https://doi.org/10.1038/s41591-023-02612-0> ;
  onco:tag "gap-fill" ;
  schema:alternateName "CLDN6" ;
  onco:targetClass "surface-antigen" ;
  onco:firstDescribed "1999"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/cldn18-2/> ;
  onco:cancers <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/testicular/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/neoantigen-mrna-vaccine/> ;
  onco:companies <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/daiichi-sankyo/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-mackensen-nat-med/> .