# OnCo record cleopatra (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/cleopatra/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "cleopatra", "NCT00567190" ;
  schema:name "CLEOPATRA"@en ;
  schema:description "Adding a second HER2 antibody, pertuzumab, extended survival by 16 months, the largest gain ever seen in metastatic breast cancer at the time."@en ;
  schema:url <https://onco.cc/trials/cleopatra/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00567190> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2008-02-12" ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:drugs <https://onco.cc/drugs/pertuzumab/>, <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/docetaxel/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:people <https://onco.cc/people/sandra-swain/>, <https://onco.cc/people/javier-cortes/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-cleopatra-n-engl-j-med-2012/>, <https://onco.cc/key-papers/paper-cleopatra-lancet-oncol-2013-update/> .