# OnCo record cobas-4800-braf-v600 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/cobas-4800-braf-v600/>
  a schema:MedicalTest ;
  onco:kind "drug" ;
  schema:identifier "cobas-4800-braf-v600" ;
  schema:name "cobas 4800 BRAF V600 Mutation Test"@en ;
  schema:description "The BRAF test for melanoma approved as companion to vemurafenib in 2011 and to cobimetinib with vemurafenib in 2016."@en ;
  schema:url <https://onco.cc/drugs/cobas-4800-braf-v600/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P110020>, <https://www.fda.gov/medical-devices/in-vitro-diagnostics/list-cleared-or-approved-companion-diagnostic-devices-in-vitro-and-imaging-tools> ;
  onco:status "approved" ;
  onco:tag "test" ;
  onco:modality "Real-time PCR companion diagnostic test (BRAF V600, melanoma tissue)" ;
  schema:alternateName "cobas 4800 BRAF V600 Mutation Test" ;
  onco:approval "US 2011: Companion diagnostic for vemurafenib in BRAF V600E melanoma", "US 2016: Companion diagnostic for cobimetinib with vemurafenib (V600E or V600K)" ;
  onco:related <https://onco.cc/drugs/thxid-braf/>, <https://onco.cc/biomarkers/braf-v600e/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/companion-diagnostic/> ;
  onco:targets <https://onco.cc/targets/braf/> ;
  onco:drugs <https://onco.cc/drugs/vemurafenib/>, <https://onco.cc/drugs/cobimetinib/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/pcr/>, <https://onco.cc/terms/companion-diagnostic-term/> .