# OnCo record cobas-egfr-mutation-test (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/cobas-egfr-mutation-test/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "cobas-egfr-mutation-test" ;
  schema:name "cobas EGFR Mutation Test v2"@en ;
  schema:description "The lung cancer gene test that became the first blood-based companion diagnostic the FDA ever approved."@en ;
  schema:url <https://onco.cc/drugs/cobas-egfr-mutation-test/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P150044> ;
  onco:status "approved" ;
  onco:tag "test" ;
  onco:modality "Real-time PCR companion diagnostic test (tissue and plasma)" ;
  schema:alternateName "cobas EGFR Mutation Test" ;
  onco:approval "US 2013: EGFR exon 19 deletion / L858R companion diagnostic for erlotinib (v1)", "US 2016: v2: T790M for osimertinib; plasma testing (first liquid biopsy companion diagnostic)" ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/companion-diagnostic/>, <https://onco.cc/technologies/liquid-biopsy/> ;
  onco:targets <https://onco.cc/targets/egfr/> ;
  onco:drugs <https://onco.cc/drugs/erlotinib/>, <https://onco.cc/drugs/osimertinib/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/companion-diagnostic-term/>, <https://onco.cc/terms/ctdna/> .