# OnCo record cold-vs-hot (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/cold-vs-hot/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "cold-vs-hot" ;
  schema:name "Hot vs cold tumours"@en ;
  schema:description "'Hot' tumours are full of immune cells and respond to immunotherapy; 'cold' tumours have kept the immune system out."@en ;
  schema:url <https://onco.cc/terms/cold-vs-hot/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tumor_microenvironment> ;
  schema:citation <https://www.cancer.gov/publications/dictionaries/cancer-terms/def/hot-tumor> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/sting-agonist/>, <https://onco.cc/technologies/oncolytic-virus/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-feig-cxcl12-fap-cafs-t-cell-exclusion-pnas-2013/>, <https://onco.cc/key-papers/paper-royal-ipilimumab-pancreatic-j-immunother-2010/>, <https://onco.cc/key-papers/paper-brahmer-anti-pd-l1-phase-1-nejm-2012/>, <https://onco.cc/key-papers/paper-oreilly-durvalumab-tremelimumab-pancreatic-jama-oncol-2019/>, <https://onco.cc/key-papers/paper-bear-pancreatic-immunotherapy-review-cancer-cell-2020/> .