# OnCo record colibactin (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/colibactin/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "colibactin" ;
  schema:name "Colibactin"@en ;
  schema:alternateName "pks island"@en, "pks+ E. coli"@en, "polyketide synthase island"@en, "SBS88"@en, "ID18"@en, "colibactin signature"@en ;
  schema:description "Colibactin is a DNA-damaging chemical made by some strains of gut bacteria. It leaves a recognisable pattern of mutations in bowel cancers, that pattern is commoner in people diagnosed young, and it is the strongest current lead on why bowel cancer is rising in the under-50s."@en ;
  schema:url <https://onco.cc/terms/colibactin/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Colibactin> ;
  schema:citation <https://doi.org/10.1038/s41586-020-2080-8>, <https://doi.org/10.1038/s41586-025-09025-8>, <https://doi.org/10.3322/caac.70067> ;
  onco:tag "gi", "colorectal" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/early-onset-colorectal/>, <https://onco.cc/cancers/colon-cancer/>, <https://onco.cc/cancers/rectal-cancer/> ;
  onco:targets <https://onco.cc/targets/apc/> ;
  onco:pathways <https://onco.cc/pathways/wnt/> ;
  onco:terms <https://onco.cc/terms/adenoma-carcinoma-sequence/>, <https://onco.cc/terms/mutational-signature/>, <https://onco.cc/terms/germline-vs-somatic/> .