# OnCo record colorectal-serrated-adenocarcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/colorectal-serrated-adenocarcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "colorectal-serrated-adenocarcinoma" ;
  schema:name "Serrated adenocarcinoma of the colon and rectum"@en ;
  schema:alternateName "Serrated adenocarcinoma"@en, "Serrated pathway colorectal cancer"@en, "Colorectal carcinoma arising from a sessile serrated lesion"@en ;
  schema:description "Serrated adenocarcinoma is a form of bowel cancer that grows out of sessile serrated polyps rather than ordinary adenomas, keeping their saw-tooth pattern. Most cases carry a KRAS or BRAF mutation and the BRAF-mutant ones are often mismatch-repair deficient. It is treated like other bowel cancer, with the BRAF and mismatch repair results guiding drugs when it has spread."@en ;
  schema:url <https://onco.cc/cancers/colorectal-serrated-adenocarcinoma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Sessile_serrated_lesion> ;
  schema:citation <https://doi.org/10.1111/his.13975>, <https://doi.org/10.1111/j.1365-2559.2011.03821.x>, <https://doi.org/10.1002/ijc.27454> ;
  onco:tag "subtype-page", "wave4", "colorectal" ;
  onco:related <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/braf-v600e-colorectal/>, <https://onco.cc/cancers/msi-high-colorectal/>, <https://onco.cc/cancers/colon-cancer/>, <https://onco.cc/cancers/colorectal-mucinous-adenocarcinoma/> ;
  onco:targets <https://onco.cc/targets/braf/>, <https://onco.cc/targets/kras/> ;
  onco:drugs <https://onco.cc/drugs/encorafenib/>, <https://onco.cc/drugs/cetuximab/> ;
  onco:standardOfCare <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/braf-v600e-colorectal/>, <https://onco.cc/drugs/encorafenib/>, <https://onco.cc/drugs/cetuximab/> .