# OnCo record comet-1 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/comet-1/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "comet-1", "NCT01605227" ;
  schema:name "COMET-1"@en ;
  schema:alternateName "COMET-1"@en, "XL184-307"@en, "cabozantinib in previously treated mCRPC"@en ;
  schema:description "A drug that made bone scans look dramatically better did not make men live longer. It is the best illustration in prostate cancer that a bone scan is not the disease."@en ;
  schema:url <https://onco.cc/trials/comet-1/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01605227>, <https://doi.org/10.1200/JCO.2015.65.5597> ;
  onco:status "negative" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/antiangiogenic/> ;
  onco:targets <https://onco.cc/targets/met/> ;
  onco:drugs <https://onco.cc/drugs/cabozantinib/>, <https://onco.cc/drugs/prednisone/> ;
  onco:companies <https://onco.cc/companies/exelixis/> ;
  onco:terms <https://onco.cc/terms/bone-metastases/>, <https://onco.cc/terms/castration-resistance/> ;
  onco:trials <https://onco.cc/trials/calgb-90401/>, <https://onco.cc/trials/tasquinimod-10tasq10/> .