# OnCo record compassion-16 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/compassion-16/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "compassion-16", "NCT04982237" ;
  schema:name "COMPASSION-16 / AK104-303"@en ;
  schema:description "A two-headed antibody that blocks two immune brakes at once extended survival in advanced cervical cancer regardless of PD-L1 status."@en ;
  schema:url <https://onco.cc/trials/compassion-16/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04982237>, <https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02135-4/abstract> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2021-08-27" ;
  onco:cancers <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/recurrent-metastatic-cervical-cancer/> ;
  onco:technologies <https://onco.cc/technologies/bispecific-antibody/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/ctla4/> ;
  onco:drugs <https://onco.cc/drugs/cadonilimab/>, <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/paclitaxel/> ;
  onco:companies <https://onco.cc/companies/akeso/> .