# OnCo record corticotroph-pitnet (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/corticotroph-pitnet/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "corticotroph-pitnet" ;
  schema:name "Corticotroph pituitary neuroendocrine tumour (Cushing disease and silent corticotroph tumour)"@en ;
  schema:alternateName "Corticotroph tumour"@en, "Corticotroph tumour (Cushing disease, silent corticotroph)"@en, "ACTH-secreting pituitary adenoma"@en, "Cushing disease"@en, "Silent corticotroph adenoma"@en, "Crooke cell tumour"@en ;
  schema:description "A corticotroph tumour is a pituitary tumour of the cells that make ACTH. When it secretes it floods the body with cortisol, causing Cushing disease (weight gain, diabetes, high blood pressure, thin skin); the silent form is found as a large non-functioning mass. Surgery through the nose is the main treatment; cortisol-lowering drugs, repeat surgery or radiotherapy follow for those not cured."@en ;
  schema:url <https://onco.cc/cancers/corticotroph-pitnet/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Cushing%27s_disease> ;
  schema:citation <https://www.cancer.gov/types/pituitary/treatment>, <https://doi.org/10.1007/s12022-022-09703-7>, <https://doi.org/10.1210/jc.2018-01956>, <https://doi.org/10.3171/2020.10.jns203236> ;
  onco:tag "subtype-page", "wave4", "rare" ;
  onco:related <https://onco.cc/cancers/pituitary-tumours/>, <https://onco.cc/cancers/lactotroph-pitnet/>, <https://onco.cc/cancers/somatotroph-pitnet/>, <https://onco.cc/cancers/gonadotroph-pitnet/>, <https://onco.cc/cancers/adrenocortical/> ;
  onco:technologies <https://onco.cc/technologies/radiosurgery-srs/> ;
  onco:drugs <https://onco.cc/drugs/osilodrostat/>, <https://onco.cc/drugs/pasireotide/>, <https://onco.cc/drugs/cabergoline/>, <https://onco.cc/drugs/mifepristone/>, <https://onco.cc/drugs/temozolomide/> ;
  onco:standardOfCare <https://onco.cc/cancers/pituitary-tumours/>, <https://onco.cc/drugs/osilodrostat/>, <https://onco.cc/drugs/pasireotide/>, <https://onco.cc/drugs/cabergoline/>, <https://onco.cc/technologies/radiosurgery-srs/>, <https://onco.cc/drugs/temozolomide/>, <https://onco.cc/drugs/mifepristone/> .