# OnCo record cox2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cox2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cox2" ;
  schema:name "COX-2 (PTGS2)"@en ;
  schema:description "COX-2 makes the inflammatory prostaglandins that help tumours grow; aspirin and celecoxib block it, which is why they reduce colorectal polyps and are studied for cancer prevention."@en ;
  schema:url <https://onco.cc/targets/cox2/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase_2>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9605>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000073756>, <https://www.uniprot.org/uniprotkb/P35354/entry>, <https://www.ncbi.nlm.nih.gov/gene/5743> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P35354/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9605>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL230> ;
  schema:alternateName "PTGS2" ;
  onco:targetClass "enzyme" ;
  onco:firstDescribed "1992"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:drugs <https://onco.cc/drugs/celecoxib/> ;
  onco:terms <https://onco.cc/terms/tumor-promoting-inflammation/>, <https://onco.cc/terms/inducing-angiogenesis/> .