# OnCo record cpx-351 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/cpx-351/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "cpx-351" ;
  schema:name "CPX-351 (liposomal daunorubicin-cytarabine)"@en ;
  schema:description "The two old chemotherapy drugs packed together into tiny fat bubbles at a fixed ratio, which doubled five-year survival in older adults with high-risk AML."@en ;
  schema:url <https://onco.cc/drugs/cpx-351/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Daunorubicin/cytarabine> ;
  owl:sameAs <http://www.wikidata.org/entity/Q62122683> ;
  schema:citation <https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(21)00134-4/abstract> ;
  onco:status "approved" ;
  onco:modality "Liposomal cytotoxic formulation" ;
  schema:alternateName "Vyxeos" ;
  onco:approval "US 2017: Newly diagnosed therapy-related AML or AML with myelodysplasia-related changes, adults", "US 2021: Paediatric patients ≥1 year" ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-secondary/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/jazz/> ;
  onco:trials <https://onco.cc/trials/cpx-351-301/> .