# OnCo record cretostimogene (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/cretostimogene/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "cretostimogene" ;
  schema:name "Cretostimogene grenadenorepvec"@en ;
  schema:description "Cretostimogene is a virus engineered to multiply only in bladder cancer cells with a broken RB pathway, instilled into the bladder. It cleared carcinoma in situ in 75% of BCG-unresponsive patients."@en ;
  schema:url <https://onco.cc/drugs/cretostimogene/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04452591> ;
  onco:status "phase-3" ;
  onco:modality "Oncolytic adenovirus (intravesical)" ;
  onco:cancers <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/non-muscle-invasive-bladder-cancer/> ;
  onco:technologies <https://onco.cc/technologies/oncolytic-virus/>, <https://onco.cc/technologies/bcg-and-intravesical-therapy/> ;
  onco:companies <https://onco.cc/companies/cg-oncology/> ;
  onco:terms <https://onco.cc/terms/bcg-unresponsive/> ;
  onco:trials <https://onco.cc/trials/bond-003/>, <https://onco.cc/trials/nct07283835/>, <https://onco.cc/trials/nct06111235/>, <https://onco.cc/trials/nct06567743/> .