# OnCo record cross-resistance (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/cross-resistance/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "cross-resistance" ;
  schema:name "Cross-resistance"@en ;
  schema:alternateName "cross-resistant"@en, "cross resistance"@en, "payload cross-resistance"@en, "cross-reactive resistance"@en, "collateral sensitivity"@en, "optimal sequencing"@en ;
  schema:description "When a cancer that has become resistant to one drug is also resistant to another it has never seen, because the two share a mechanism. It is the central worry in deciding the order (sequencing) of similar drugs."@en ;
  schema:url <https://onco.cc/terms/cross-resistance/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Cross-resistance> ;
  schema:citation <https://en.wikipedia.org/wiki/Cross-resistance> ;
  onco:related <https://onco.cc/terms/adc-sequencing/>, <https://onco.cc/terms/resistance/>, <https://onco.cc/terms/rechallenge/>, <https://onco.cc/terms/first-line/> ;
  onco:sections <https://onco.cc/fronts/adcs/>, <https://onco.cc/fronts/targeted-therapy/> ;
  onco:technologies <https://onco.cc/technologies/adc/> .