# OnCo record cross-then-nivolumab (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/cross-then-nivolumab/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "cross-then-nivolumab" ;
  schema:name "CROSS chemoradiation → surgery → adjuvant nivolumab if residual disease"@en ;
  schema:description "Chemotherapy and radiation, then surgery, then a year of immunotherapy if the operation shows cancer was still there. This is the current curative-intent pathway."@en ;
  schema:url <https://onco.cc/pairings/cross-then-nivolumab/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02743494> ;
  onco:cancers <https://onco.cc/cancers/esophageal/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/> ;
  onco:terms <https://onco.cc/terms/neoadjuvant-adjuvant/>, <https://onco.cc/terms/clinical-complete-response/> ;
  onco:trials <https://onco.cc/trials/cross/>, <https://onco.cc/trials/checkmate-577/>, <https://onco.cc/trials/sano/> ;
  onco:pairs <https://onco.cc/trials/cross/>, <https://onco.cc/drugs/nivolumab/> .