# OnCo record cross (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/cross/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "cross", "NTR487" ;
  schema:name "CROSS"@en ;
  schema:description "The trial that made chemotherapy plus radiation before surgery the standard for oesophageal cancer; the survival gain was still there ten years later."@en ;
  schema:url <https://onco.cc/trials/cross/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://www.nejm.org/doi/full/10.1056/NEJMoa1112088>, <https://ascopubs.org/doi/10.1200/JCO.20.03614> ;
  onco:status "positive" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/oesophageal-squamous-cell-carcinoma/>, <https://onco.cc/cancers/oesophageal-adenocarcinoma/>, <https://onco.cc/cancers/gastric/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/platinum/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/radiosensitisers/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/> ;
  onco:terms <https://onco.cc/terms/neoadjuvant-adjuvant/>, <https://onco.cc/terms/pcr/>, <https://onco.cc/terms/chemoradiation/> ;
  onco:people <https://onco.cc/people/jan-van-lanschot/>, <https://onco.cc/people/kitagawa-yuko/> .