# OnCo record crown (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/crown/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "crown", "NCT03052608" ;
  schema:name "CROWN"@en ;
  schema:description "The trial with the longest disease control ever seen for a targeted lung cancer pill: most patients still progression-free at five years."@en ;
  schema:url <https://onco.cc/trials/crown/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03052608> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2017-04-27" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/secondary-brain-tumours/>, <https://onco.cc/cancers/alk-positive-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/alk/> ;
  onco:drugs <https://onco.cc/drugs/lorlatinib/> ;
  onco:companies <https://onco.cc/companies/pfizer/> ;
  onco:people <https://onco.cc/people/ross-camidge/>, <https://onco.cc/people/solomon-benjamin/>, <https://onco.cc/people/ahn-myung-ju/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-shaw-crown-lorlatinib-crizotinib-nejm-2020/>, <https://onco.cc/key-papers/paper-crown-lancet-respir-med-2023-update/> .