# OnCo record crs-grading-and-management (protocol). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: .
@prefix onco: .
@prefix xsd: .
a schema:MedicalGuideline ;
onco:kind "protocol" ;
schema:identifier "crs-grading-and-management" ;
schema:name "Cytokine release syndrome after CAR T-cell therapy: ASTCT grading, tocilizumab and steroids"@en ;
schema:alternateName "CRS management"@en, "cytokine release syndrome grading"@en, "ASTCT CRS grading"@en, "tocilizumab for CRS"@en, "CAR-T fever"@en ;
schema:description "After CAR T-cell therapy, the immune cells can release a flood of chemical messengers, causing fever, low blood pressure and breathing trouble: cytokine release syndrome. Any fever after CAR T-cell therapy needs the treating centre at once. Teams grade it from 1 to 4 and treat with tocilizumab and, if needed, steroids; infection is treated at the same time because the two look alike."@en ;
schema:url ;
schema:dateModified "2026-11-11"^^xsd:date ;
onco:tag "protocol", "cell-therapy", "car-t", "acute-oncology" ;
onco:related ;
onco:technologies ;
onco:drugs , , , , , , , , , , ;
onco:institutions ;
onco:terms , .