# OnCo record ctdna-mrd-positive (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/ctdna-mrd-positive/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "ctdna-mrd-positive" ;
  schema:name "ctDNA MRD positivity (molecular residual disease after curative treatment)"@en ;
  schema:alternateName "ctDNA MRD"@en, "ctDNA positive"@en, "ctDNA-positive"@en, "molecular residual disease"@en, "MRD-positive ctDNA"@en, "Signatera positive"@en, "ctDNA detected after surgery"@en ;
  schema:description "A ctDNA MRD test looks for the tumour's own mutations in blood after surgery. Detection predicts relapse months before scans, and in 2026 the FDA approved Signatera as the companion test selecting bladder cancer patients for adjuvant atezolizumab."@en ;
  schema:url <https://onco.cc/biomarkers/ctdna-mrd-positive/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.fda.gov/medical-devices/in-vitro-diagnostics/list-cleared-or-approved-companion-diagnostic-devices-in-vitro-and-imaging-tools>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6fa682c9-a312-4932-9831-f286908660ee> ;
  onco:tag "biomarker", "genome-wide", "ctdna" ;
  onco:related <https://onco.cc/biomarkers/tmb-high/>, <https://onco.cc/biomarkers/esr1-mutation-ctdna/> ;
  onco:cancers <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:drugs <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/signatera/>, <https://onco.cc/drugs/guardant-reveal/>, <https://onco.cc/drugs/radar-mrd/>, <https://onco.cc/drugs/oncodetect/>, <https://onco.cc/drugs/clonoseq/> ;
  onco:terms <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/tumour-informed-assay/>, <https://onco.cc/terms/cfdna/> .