# OnCo record ctdna (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/ctdna/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "ctdna" ;
  schema:name "Circulating tumour DNA (ctDNA)"@en ;
  schema:alternateName "circulating tumor DNA"@en, "ctDNA-positive"@en, "ctDNA-negative"@en, "ctDNA-based"@en, "ctDNA-directed"@en, "tumour fraction"@en ;
  schema:description "Circulating tumour DNA (ctDNA) consists of fragments of DNA shed by tumour cells into the blood, detectable with sensitive sequencing."@en ;
  schema:url <https://onco.cc/terms/ctdna/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Circulating_tumor_DNA> ;
  owl:sameAs <http://www.wikidata.org/entity/Q19596321> ;
  schema:citation <https://en.wikipedia.org/wiki/Circulating_tumor_DNA> ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/mced/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-leighl-nile-cfdna-tissue-genotyping-ccr-2019/>, <https://onco.cc/key-papers/paper-aggarwal-plasma-genotyping-personalised-therapy-jama-oncol-2019/>, <https://onco.cc/key-papers/paper-oxnard-osimertinib-resistance-mechanisms-jama-oncol-2018/>, <https://onco.cc/key-papers/paper-lindeman-lung-molecular-testing-guideline-jto-2018/>, <https://onco.cc/key-papers/paper-wyatt-ctdna-tissue-concordance-mcrpc-jnci-2017/>, <https://onco.cc/key-papers/paper-tukachinsky-ctdna-3334-advanced-prostate-ccr-2021/>, <https://onco.cc/key-papers/paper-annala-ctdna-resistance-abiraterone-enzalutamide-cancer-discov-2018/> .