# OnCo record ctnnb1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ctnnb1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ctnnb1" ;
  schema:name "CTNNB1"@en ;
  schema:alternateName "catenin beta 1"@en, "Catenin beta-1"@en, "beta-catenin"@en, "armadillo"@en, "CTNNB"@en, "CTNNB1" ;
  schema:description "CTNNB1 (Catenin beta-1) is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor, a biomarker and a fusion partner, and an approved or late-stage drug is recorded against it. Tied to Hepatocellular carcinoma, Colorectal cancer, Ovarian cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/ctnnb1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2514>, <https://www.uniprot.org/uniprotkb/P35222/entry>, <https://www.ncbi.nlm.nih.gov/gene/1499>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000168036> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2514>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000168036>, <https://www.uniprot.org/uniprotkb/P35222/entry>, <https://www.ncbi.nlm.nih.gov/gene/1499> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/adrenocortical/> ;
  onco:drugs <https://onco.cc/drugs/nirogacestat/> ;
  onco:pathways <https://onco.cc/pathways/endometrial-cancer-signalling/>, <https://onco.cc/pathways/hepatocellular-carcinoma-signalling/> .