# OnCo record custirsen (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/custirsen/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "custirsen" ;
  schema:name "Custirsen"@en ;
  schema:alternateName "OGX-011"@en, "TV-1011"@en ;
  schema:description "A drug designed to switch off a protein that helps cancer cells survive chemotherapy. Two large trials found it added nothing."@en ;
  schema:url <https://onco.cc/drugs/custirsen/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S1470-2045(17)30168-7>, <https://doi.org/10.1016/S1470-2045(17)30605-8> ;
  onco:status "withdrawn" ;
  onco:modality "antisense oligonucleotide" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/antisense-sirna/> ;
  onco:companies <https://onco.cc/companies/achieve-life-sciences/> ;
  onco:terms <https://onco.cc/terms/castration-resistance/> ;
  onco:trials <https://onco.cc/trials/synergy-custirsen/>, <https://onco.cc/trials/affinity-custirsen/> .