# OnCo record cxcr4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cxcr4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cxcr4" ;
  schema:name "CXCR4"@en ;
  schema:description "A chemokine receptor that anchors blood cells in the marrow and helps cancer cells home to it; mutated in a third of Waldenström patients and targeted by plerixafor for stem-cell mobilisation."@en ;
  schema:url <https://onco.cc/targets/cxcr4/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/CXCR4>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2561>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000121966>, <https://www.uniprot.org/uniprotkb/P61073/entry>, <https://www.ncbi.nlm.nih.gov/gene/7852> ;
  owl:sameAs <http://www.wikidata.org/entity/Q415718> ;
  schema:citation <https://doi.org/10.1182/blood-2014-01-550905> ;
  onco:tag "gap-fill" ;
  schema:alternateName "CXCR4" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1993"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/waldenstrom/>, <https://onco.cc/cancers/multiple-myeloma/>, <https://onco.cc/cancers/aml/> ;
  onco:technologies <https://onco.cc/technologies/autologous-stem-cell-transplant/>, <https://onco.cc/technologies/radioligand-therapy/> ;
  onco:drugs <https://onco.cc/drugs/mavorixafor/>, <https://onco.cc/drugs/plerixafor/> ;
  onco:terms <https://onco.cc/terms/theranostics/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-treon-blood/> .