# OnCo record cyclin-d1-t11-14 (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/cyclin-d1-t11-14/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "cyclin-d1-t11-14" ;
  schema:name "t(11;14), cyclin D1 and SOX11"@en ;
  schema:alternateName "t(11;14)(q13;q32)"@en, "CCND1 translocation"@en, "CCND1::IGH"@en, "IGH::CCND1"@en, "cyclin D1"@en, "cyclin D1 immunohistochemistry"@en, "cyclin D1-positive"@en, "cyclin D1-negative mantle cell lymphoma"@en, "SOX11"@en, "SOX11-negative"@en, "leukaemic non-nodal mantle cell lymphoma"@en, "t(11;14) myeloma"@en, "CCND1-translocated myeloma"@en ;
  schema:description "The t(11;14) translocation parks the cyclin D1 gene next to the antibody gene's accelerator, flooding the cell with a protein that pushes it through division; a brown nuclear stain for cyclin D1 (plus SOX11) is how mantle cell lymphoma is confirmed, and in myeloma the same translocation marks the patients who respond to venetoclax."@en ;
  schema:url <https://onco.cc/terms/cyclin-d1-t11-14/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Cyclin_D1> ;
  schema:citation <https://en.wikipedia.org/wiki/Cyclin_D1> ;
  onco:related <https://onco.cc/terms/mipi/>, <https://onco.cc/targets/bcl2/>, <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/terms/fish/>, <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/cytogenetics/>, <https://onco.cc/targets/cdk4-6/>, <https://onco.cc/terms/high-risk-myeloma/>, <https://onco.cc/drugs/ibrutinib/> ;
  onco:cancers <https://onco.cc/cancers/mantle-cell-lymphoma/>, <https://onco.cc/cancers/plasma-cell-leukaemia/>, <https://onco.cc/cancers/myeloma-relapsed-refractory/> .