# OnCo record cyclophosphamide (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/cyclophosphamide/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "cyclophosphamide" ;
  schema:name "Cyclophosphamide"@en ;
  schema:description "Cyclophosphamide is an alkylating chemotherapy that damages DNA in dividing cells. It is part of CHOP for lymphoma, AC for breast cancer and VAC for childhood sarcomas, clears lymphocytes before CAR-T and prevents graft-versus-host disease after transplant; bladder bleeding, infertility and secondary leukaemia are its harms."@en ;
  schema:url <https://onco.cc/drugs/cyclophosphamide/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Cyclophosphamide> ;
  owl:sameAs <http://www.wikidata.org/entity/Q408524> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=cyclophosphamide> ;
  onco:status "approved" ;
  onco:tag "gap-fill", "generic", "who-essential" ;
  onco:modality "Alkylating agent (oxazaphosphorine prodrug)" ;
  schema:alternateName "Cytoxan / Endoxan" ;
  onco:approval "US 1959: Lymphomas, leukaemias, multiple myeloma, breast, ovarian, neuroblastoma, retinoblastoma and other cancers" ;
  onco:related <https://onco.cc/drugs/mesna/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/ewing-sarcoma/>, <https://onco.cc/cancers/rhabdomyosarcoma/>, <https://onco.cc/cancers/neuroblastoma/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/multiple-myeloma/>, <https://onco.cc/cancers/pancreatic/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/allogeneic-hsct/> ;
  onco:trials <https://onco.cc/trials/dbcg-82bc/>, <https://onco.cc/trials/nct06097364/>, <https://onco.cc/trials/nct04529772/>, <https://onco.cc/trials/nct06717347/>, <https://onco.cc/trials/nct06911502/>, <https://onco.cc/trials/nct06413498/>, <https://onco.cc/trials/nct06091865/>, <https://onco.cc/trials/nct06091254/>, <https://onco.cc/trials/nct06045806/>, <https://onco.cc/trials/nct05888493/>, <https://onco.cc/trials/nct05371093/>, <https://onco.cc/trials/nct03407144/>, <https://onco.cc/trials/nct04663347/>, <https://onco.cc/trials/nct04542824/>, <https://onco.cc/trials/nct06480565/>, <https://onco.cc/trials/nct04792489/>, <https://onco.cc/trials/nct06253663/>, <https://onco.cc/trials/nct07124936/>, <https://onco.cc/trials/nct03709680/>, <https://onco.cc/trials/nct05826535/>, <https://onco.cc/trials/nct05201248/>, <https://onco.cc/trials/nct07589543/>, <https://onco.cc/trials/nct04920617/>, <https://onco.cc/trials/nct07730515/>, <https://onco.cc/trials/nct07510815/>, <https://onco.cc/trials/nct07617753/>, <https://onco.cc/trials/nct03907852/>, <https://onco.cc/trials/nct07149857/>, <https://onco.cc/trials/nct07617805/>, <https://onco.cc/trials/nct06119685/>, <https://onco.cc/trials/nct07480928/>, <https://onco.cc/trials/nct05283720/>, <https://onco.cc/trials/nct04245839/>, <https://onco.cc/trials/nct03836352/>, <https://onco.cc/trials/nct06093841/>, <https://onco.cc/trials/nct07627711/>, <https://onco.cc/trials/nct04836507/>, <https://onco.cc/trials/nct06564038/>, <https://onco.cc/trials/nct07500220/>, <https://onco.cc/trials/nct07627698/>, <https://onco.cc/trials/nct07641036/>, <https://onco.cc/trials/nct04416984/>, <https://onco.cc/trials/nct03725059/>, <https://onco.cc/trials/nct07523529/>, <https://onco.cc/trials/nct07502287/>, <https://onco.cc/trials/nct05624554/>, <https://onco.cc/trials/nct05999994/>, <https://onco.cc/trials/nct06389006/>, <https://onco.cc/trials/nct06966700/>, <https://onco.cc/trials/nct06797635/>, <https://onco.cc/trials/nct06112379/>, <https://onco.cc/trials/nct05406401/>, <https://onco.cc/trials/nct07598955/>, <https://onco.cc/trials/nct04623541/>, <https://onco.cc/trials/nct06890884/>, <https://onco.cc/trials/nct05673785/>, <https://onco.cc/trials/nct04390399/>, <https://onco.cc/trials/nct06500273/>, <https://onco.cc/trials/nct06947967/>, <https://onco.cc/trials/nct06425302/>, <https://onco.cc/trials/nct07551362/>, <https://onco.cc/trials/nct06072612/>, <https://onco.cc/trials/eclipse/> .