# OnCo record dacarbazine (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/dacarbazine/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "dacarbazine" ;
  schema:name "Dacarbazine"@en ;
  schema:alternateName "DTIC"@en, "DTIC-Dome (historic)" ;
  schema:description "Dacarbazine is an older chemotherapy infusion. It was the standard treatment for advanced melanoma for decades and is the D in the ABVD regimen that cures most Hodgkin lymphoma."@en ;
  schema:url <https://onco.cc/drugs/dacarbazine/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Dacarbazine> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=dacarbazine>, <https://www.cancer.gov/about-cancer/treatment/drugs/dacarbazine> ;
  onco:status "approved" ;
  onco:tag "nci-list", "generic" ;
  onco:modality "Alkylating agent (triazene)" ;
  onco:approval "US 1975: Metastatic malignant melanoma; Hodgkin disease (second line, combination)" ;
  onco:related <https://onco.cc/drugs/temozolomide/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/hodgkin-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:trials <https://onco.cc/trials/nct03016819/>, <https://onco.cc/trials/nct05987332/>, <https://onco.cc/trials/nct06703398/>, <https://onco.cc/trials/nct03407144/>, <https://onco.cc/trials/nct04733183/>, <https://onco.cc/trials/nct07310784/>, <https://onco.cc/trials/nct02979522/> .