# OnCo record ddgp-vs-smile-enktl (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/ddgp-vs-smile-enktl/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "ddgp-vs-smile-enktl", "NCT01501149" ;
  schema:name "DDGP versus SMILE"@en ;
  schema:alternateName "CTTNKTL-III/IV"@en, "DDGP regimen"@en, "Pegaspargase-based versus L-asparaginase-based chemotherapy in advanced NK/T-cell lymphoma"@en ;
  schema:description "In advanced NK/T-cell lymphoma, a gentler regimen built on pegylated asparaginase kept the disease controlled for longer than SMILE, the regimen it was compared with, and caused fewer dangerously low white cell counts."@en ;
  schema:url <https://onco.cc/trials/ddgp-vs-smile-enktl/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01501149>, <https://doi.org/10.1001/jamaoncol.2022.1968> ;
  onco:status "positive" ;
  onco:tag "lymphoma-evidence-entities" ;
  onco:phase "4" ;
  schema:startDate "2011-01" ;
  onco:cancers <https://onco.cc/cancers/extranodal-nk-t-cell-lymphoma/>, <https://onco.cc/cancers/peripheral-t-cell-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/asparaginase/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/etoposide/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/orr/>, <https://onco.cc/terms/hazard-ratio/> ;
  onco:trials <https://onco.cc/trials/smile-enktl/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-ddgp-vs-smile-nk-t-cell-lymphoma-jama-oncol-2022/>, <https://onco.cc/key-papers/paper-ddgp-vs-smile-nk-t-cell-lymphoma-clin-cancer-res-2016/> .