# OnCo record ddx41-myeloid-predisposition (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/ddx41-myeloid-predisposition/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "ddx41-myeloid-predisposition" ;
  schema:name "DDX41-associated predisposition to myeloid neoplasms"@en ;
  schema:alternateName "DDX41 syndrome"@en, "germline DDX41"@en, "DDX41-related hematologic malignancy predisposition syndrome"@en ;
  schema:description "An inherited fault in the DDX41 gene is the commonest known inherited cause of myelodysplastic syndrome and acute myeloid leukaemia, and it usually shows itself in older adults rather than children. Finding it matters for treatment and for choosing a family stem cell donor."@en ;
  schema:url <https://onco.cc/terms/ddx41-myeloid-predisposition/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/1078-0432.ccr-24-0685>, <https://www.orpha.net/en/disease/detail/488647> ;
  onco:tag "gap-fill", "hereditary" ;
  onco:related <https://onco.cc/terms/germline-myeloid-predisposition/> ;
  onco:cancers <https://onco.cc/cancers/mds/>, <https://onco.cc/cancers/aml/> ;
  onco:technologies <https://onco.cc/technologies/allogeneic-hsct/>, <https://onco.cc/technologies/germline-testing/> ;
  onco:targets <https://onco.cc/targets/ddx41/> ;
  onco:terms <https://onco.cc/terms/hereditary-cancer-syndromes/> .