# OnCo record de-escalate-iadt (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/de-escalate-iadt/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "de-escalate-iadt", "NCT05974774" ;
  schema:name "DE-ESCALATE (EORTC trial of intermittent androgen deprivation with AR pathway inhibitors)"@en ;
  schema:alternateName "Intermittent Androgen Deprivation Therapy in the Era of AR Pathway Inhibitors"@en, "EORTC DE-ESCALATE"@en ;
  schema:description "A large European trial asking whether men with prostate cancer that has spread, who respond well to modern hormone treatment, can take planned breaks from it without shortening their lives, with fewer side effects and lower cost."@en ;
  schema:url <https://onco.cc/trials/de-escalate-iadt/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05974774>, <https://cordis.europa.eu/project/id/101104574> ;
  onco:status "recruiting" ;
  onco:phase "3" ;
  schema:startDate "2025-05-23" ;
  onco:cancers <https://onco.cc/cancers/prostate-mhspc/>, <https://onco.cc/cancers/prostate/> ;
  onco:companies <https://onco.cc/companies/curie-nki-eortc/> ;
  onco:institutions <https://onco.cc/institutions/eu-mission-on-cancer/> ;
  onco:terms <https://onco.cc/terms/intermittent-androgen-deprivation/>, <https://onco.cc/terms/adt/>, <https://onco.cc/terms/de-escalation/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/>, <https://onco.cc/bottlenecks/b-drug-pricing/> .