# OnCo record de-escalate (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/de-escalate/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "de-escalate", "NCT01874171" ;
  schema:name "De-ESCALaTE HPV"@en ;
  schema:description "De-ESCALaTE, the European counterpart of RTOG 1016, found that cetuximab gave no less toxicity than cisplatin and worse tumour control in HPV-positive throat cancer."@en ;
  schema:url <https://onco.cc/trials/de-escalate/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01874171>, <https://doi.org/10.1016/S0140-6736(18)32752-1> ;
  onco:status "negative" ;
  onco:tag "radiation-wave4" ;
  onco:phase "3" ;
  schema:startDate "2012-11-15" ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/oropharyngeal-cancer/>, <https://onco.cc/cancers/hpv-positive-oropharyngeal-cancer/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/cetuximab/> ;
  onco:terms <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/technologies/hpv-testing/> .