# OnCo record dedifferentiated-chordoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/dedifferentiated-chordoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "dedifferentiated-chordoma" ;
  schema:name "Dedifferentiated chordoma"@en ;
  schema:alternateName "Chordoma with sarcomatous transformation"@en, "Dedifferentiated chordoma (high-grade sarcoma in a chordoma)"@en ;
  schema:description "Dedifferentiated chordoma is a rare form of chordoma in which part of the tumour has turned into a high-grade sarcoma, usually after recurrence or radiotherapy but sometimes from the start. The sarcoma component decides the outcome, which is much worse than ordinary chordoma, so it is treated with surgery and the chemotherapy used for high-grade sarcomas, not surgery and radiotherapy alone."@en ;
  schema:url <https://onco.cc/cancers/dedifferentiated-chordoma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Chordoma> ;
  schema:citation <https://doi.org/10.1097/pas.0000000000001501>, <https://doi.org/10.1302/0301-620x.90b5.20365> ;
  onco:tag "subtype-page", "wave4", "rare" ;
  onco:related <https://onco.cc/cancers/chordoma/>, <https://onco.cc/cancers/poorly-differentiated-chordoma/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/undifferentiated-pleomorphic-sarcoma/> ;
  onco:technologies <https://onco.cc/technologies/proton-therapy/> ;
  onco:targets <https://onco.cc/targets/tbxt/> ;
  onco:drugs <https://onco.cc/drugs/doxorubicin/> ;
  onco:standardOfCare <https://onco.cc/cancers/chordoma/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/technologies/proton-therapy/>, <https://onco.cc/drugs/doxorubicin/> .