# OnCo record degrader-antibody-conjugate (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/degrader-antibody-conjugate/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "degrader-antibody-conjugate" ;
  schema:name "Degrader-antibody conjugate (DAC)"@en ;
  schema:description "An ADC that delivers a protein-destroying molecule instead of chemotherapy, hitting targets inside the cell that were previously unreachable."@en ;
  schema:url <https://onco.cc/technologies/degrader-antibody-conjugate/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1073/pnas.141230798> ;
  onco:status "phase-1" ;
  onco:tag "frontier" ;
  onco:sections <https://onco.cc/fronts/adcs/>, <https://onco.cc/fronts/targeted-therapy/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/protac-degrader/> ;
  onco:companies <https://onco.cc/companies/cullgen/>, <https://onco.cc/companies/firefly-bio/>, <https://onco.cc/companies/orum-therapeutics/>, <https://onco.cc/companies/prelude-therapeutics/> ;
  onco:dependsOn <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/protac-degrader/> .