# OnCo record del17p-tp53 (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/del17p-tp53/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "del17p-tp53" ;
  schema:name "del(17p) / TP53 aberration in CLL"@en ;
  schema:description "A del(17p) deletion or TP53 mutation means loss or damage of the p53 safety gene in CLL. These patients should never get chemotherapy; they need BTK inhibitors or venetoclax, usually continuously."@en ;
  schema:url <https://onco.cc/terms/del17p-tp53/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia> ;
  schema:citation <https://clinicaltrials.gov/study/NCT03336333>, <https://clinicaltrials.gov/study/NCT03836261> ;
  onco:cancers <https://onco.cc/cancers/cll/> ;
  onco:technologies <https://onco.cc/technologies/cytogenetics-fish/> ;
  onco:targets <https://onco.cc/targets/tp53/> ;
  onco:trials <https://onco.cc/trials/sequoia/>, <https://onco.cc/trials/amplify/> .