# OnCo record diethylstilbestrol (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/diethylstilbestrol/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "diethylstilbestrol" ;
  schema:name "Diethylstilbestrol"@en ;
  schema:alternateName "DES"@en, "Stilboestrol"@en, "Honvan (fosfestrol)"@en, "Stilbestrol" ;
  schema:description "Diethylstilbestrol was the first hormonal treatment for prostate cancer, standard from the 1940s, and was also given for breast cancer, before its cardiovascular harms and the cancers it caused in the daughters of women who took it in pregnancy ended its use."@en ;
  schema:url <https://onco.cc/drugs/diethylstilbestrol/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Diethylstilbestrol> ;
  schema:citation <https://en.wikipedia.org/wiki/Diethylstilbestrol>, <https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL411> ;
  onco:status "historic" ;
  onco:tag "gap-fill", "chembl-universe" ;
  onco:modality "Oral small-molecule synthetic oestrogen" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/endocrine-therapy/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/> ;
  onco:trials <https://onco.cc/trials/nct00316927/> .
