# OnCo record diindolylmethane-dim (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/diindolylmethane-dim/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "diindolylmethane-dim" ;
  schema:name "Diindolylmethane (DIM)"@en ;
  schema:alternateName "DIM"@en, "3,3'-diindolylmethane"@en ;
  schema:description "DIM is a broccoli-derived compound sold to 'balance oestrogen'. In a randomised trial in women taking tamoxifen for breast cancer, it lowered the blood level of endoxifen, the form of tamoxifen that does most of the work, so it should not be taken alongside tamoxifen without the oncologist's agreement."@en ;
  schema:url <https://onco.cc/technologies/diindolylmethane-dim/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://www.mskcc.org/cancer-care/integrative-medicine/herbs/diindolylmethane> ;
  onco:status "phase-2" ;
  onco:tag "complementary", "supportive-care", "evidence:harm" ;
  onco:related <https://onco.cc/technologies/indole-3-carbinol/>, <https://onco.cc/technologies/dhea-supplements/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/prostate/> ;
  onco:sections <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/hormonal/>, <https://onco.cc/fronts/prevention/> ;
  onco:technologies <https://onco.cc/technologies/integrative-oncology/>, <https://onco.cc/technologies/dietary-supplements-treatment-interactions/>, <https://onco.cc/technologies/endocrine-therapy/> ;
  onco:drugs <https://onco.cc/drugs/tamoxifen/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/> .
