# OnCo record dolasetron (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/dolasetron/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "dolasetron" ;
  schema:name "Dolasetron"@en ;
  schema:alternateName "Dolasetron mesylate"@en, "Anzemet" ;
  schema:description "Dolasetron is one of the serotonin-blocking antiemetics that transformed chemotherapy in the 1990s, approved in 1997 to prevent nausea and vomiting; its intravenous form lost its chemotherapy indication in 2010 because of heart rhythm effects."@en ;
  schema:url <https://onco.cc/drugs/dolasetron/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Dolasetron> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=dolasetron>, <https://en.wikipedia.org/wiki/Dolasetron>, <https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200880> ;
  onco:status "established" ;
  onco:tag "gap-fill", "chembl-universe" ;
  onco:modality "Oral 5-HT3 receptor antagonist antiemetic" ;
  onco:approval "US 1997: Prevention of nausea and vomiting from moderately emetogenic chemotherapy (oral); intravenous chemotherapy indication removed in 2010" ;
  onco:targets <https://onco.cc/targets/htr3a/> ;
  onco:drugs <https://onco.cc/drugs/ondansetron/>, <https://onco.cc/drugs/granisetron/>, <https://onco.cc/drugs/palonosetron/> .