# OnCo record dot1l (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/dot1l/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "dot1l" ;
  schema:name "DOT1L"@en ;
  schema:alternateName "DOT1 like histone lysine methyltransferase"@en, "Histone-lysine N-methyltransferase, H3 lysine-79 specific"@en, "KIAA1814"@en, "DOT1"@en, "KMT4"@en, "DOT1L" ;
  schema:description "DOT1L (Histone-lysine N-methyltransferase, H3 lysine-79 specific) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Diffuse large B-cell lymphoma and Neuroblastoma."@en ;
  schema:url <https://onco.cc/targets/dot1l/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:24948>, <https://www.uniprot.org/uniprotkb/Q8TEK3/entry>, <https://www.ncbi.nlm.nih.gov/gene/84444>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104885> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:24948>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104885>, <https://www.uniprot.org/uniprotkb/Q8TEK3/entry>, <https://www.ncbi.nlm.nih.gov/gene/84444> ;
  onco:related <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/neuroblastoma/> ;
  onco:pathways <https://onco.cc/pathways/menin-kmt2a/> .