# OnCo record dreamseq (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/dreamseq/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "dreamseq", "NCT02224781" ;
  schema:name "DREAMseq (ECOG-ACRIN EA6134)"@en ;
  schema:description "Settled the order question: for BRAF-mutant melanoma, start with immunotherapy and save the targeted pills for later."@en ;
  schema:url <https://onco.cc/trials/dreamseq/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02224781>, <https://ascopubs.org/doi/10.1200/JCO.22.01763> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2015-09-08" ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/braf-v600-melanoma/>, <https://onco.cc/cancers/advanced-melanoma/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/braf/>, <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/ctla4/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/ipilimumab/>, <https://onco.cc/drugs/dabrafenib-trametinib/> ;
  onco:companies <https://onco.cc/companies/ecog-acrin/> .