# OnCo record drug-response-sensitivity (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/drug-response-sensitivity/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "drug-response-sensitivity" ;
  schema:name "Drug response and drug sensitivity (IC50, AUC)"@en ;
  schema:alternateName "drug sensitivity"@en, "drug response prediction"@en, "cell-line drug sensitivity"@en, "IC50"@en, "half maximal inhibitory concentration"@en, "dose-response AUC"@en, "area under the dose-response curve"@en, "GI50"@en, "AAC"@en ;
  schema:description "Drug sensitivity is how strongly a tumour or cell line is held back by a compound; it is summarised by the concentration that halves growth (IC50) or by the area under the whole dose-response curve."@en ;
  schema:url <https://onco.cc/terms/drug-response-sensitivity/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/IC50> ;
  schema:citation <https://doi.org/10.1093/nar/gks1111>, <https://en.wikipedia.org/wiki/IC50> ;
  onco:tag "cansim-terms" ;
  onco:related <https://onco.cc/collections/depmap/>, <https://onco.cc/terms/cancer-ai-vocabulary/> ;
  onco:terms <https://onco.cc/terms/pharmacogenomics-term/>, <https://onco.cc/terms/cell-lines-as-proxy/> .